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CREATININE
Creatinine is a waste product that comes from the
normal wear and tear on muscles of the body.
Everyone has creatinine in their bloodstream
A creatinine test is used to see if your kidneys are working normally.
It's often ordered along with another kidney test called blood urea nitrogen (BUN) or as part of a comprehensive metabolic panel (CMP).
Serum creatinine (Scr) is the most commonly used biomarker of kidney function. In the steady-state, serum creatinine can be used to estimate glomerular filtration rate, using the modification of diet in renal disease (MDRD) [1] or chronic kidney disease epidemiology collaboration formulae.
Doses up to 25 grams daily for up to 14 days have been safely used. Lower doses up to 4-5 grams taken daily for up to 18 months have also been safely used. Creatine is POSSIBLY SAFE when taken by mouth, long-term. Doses up to 10 grams daily for up to 5 years have been safely used.
Estimating kidney function is challenging and critically ill patients.
Creatinine is a widely used functional biomarker and has substantial shortcomings.
Use of novel functional biomarkers with creatinine provides additional information.
Creatinine could be used for the estimation of muscle mass or clinical outcomes.
New technologies for direct GFR measurement could overcome creatinine limitations.
New technologies for direct GFR measurement could overcome creatinine limitations.Estimating kidney function is challenging and critically ill patients.
•
Creatinine is a widely used functional biomarker and has substantial shortcomings.
•
Use of novel functional biomarkers with creatinine provides additional information.
•
Creatinine could be used for the estimation of muscle mass or clinical outcomes.
•
New technologies for direct GFR measurement could overcome creatinine limitations.