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ISATIN AR
These chemical reactions form the basis for the synthesis of other biologically important derivatives such as tryptanthrin, indirubins, and 2-oxindoles. Isatin derivatives also have various industrial applications for example, they are used as corrosion inhibitors, as fluorescent sensors and also in the dye industry.
These chemical reactions form the basis for the synthesis of other biologically important derivatives such as tryptanthrin, indirubins, and 2-oxindoles. Isatin derivatives also have various industrial applications; for example, they are used as corrosion inhibitors, as fluorescent sensors and also in the dye industry.
Administration of the compound with a single dose of 50 and 100 mg kg−1
Isatin forms a blue dye (indophenin) if it is mixed with sulfuric acid and crude benzene. It is used as a reference material in the preparation of indigo and Maya Blue. It is also responsible for the yellow color exhibited by the "Maya Yellow" pigment.
Reactant for preparation of:
- Phthalazinone derivatives
- Spirooxindole derivatives
- Agents against multidrug-resistant cells expressing P-glycoprotein
- Thiazolidinones spiro-fused to indolin-2-ones as potent and selective inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B
- Triazole-isatine compounds as potential antibacterial and antifungal agents
- Biologically relevant scaffolds such as spiro[indole-thiazolidinones]
Reactant for:
- Cascade reactions with heterocyclic ketene aminals
- Knoevenagel condensation reactions