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CHAPSO FOR BIOCHEMISTRY
"Liposome Solubilization and Membrane Protein Reconstitution Using Chaps and Chapso". European Journal of Biochemistry.These detergents are also widely used to solubilize chromophores or to stabilize enzymes in diagnostic analyses and biochemical assays.
Chapso has been used in a study to assess methods for high-throughput crystallization of membrane proteins. It has also been used in a study to investigate the effects of detergents on the structure of rhomboid proteases in a lipid environment.
A nondenaturing zwitterionic detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.
A nondenaturing zwitterionic detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.Chapso has been used in a study to assess methods for high-throughput crystallization of membrane proteins. It has also been used in a study to investigate the effects of detergents on the structure of rhomboid proteases in a lipid environment.
A nondenaturing zwitterionic detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.
Children up to 1 year of age—Use is not recommended.For oral dosage form (oral suspension):
For treatment of poisoning:
Adults and teenagers—Dose is usually 50 to 100 grams of activated charcoal given one time.
Children 1 through 12 years of age—Dose is usually 25 to 50 grams of activated charcoal given one time.
Children up to 1 year of age—Use is not recommended.
Children up to 1 year of age—Dose is usually 10 to 25 grams mixed with water, or the dose may be based on body weight. It may be 0.5 to 1 gram per kg (0.23 to 0.45 gram per pound) of body weight mixed with water.For oral dosage form (powder):
For treatment of poisoning:
Treatment with one dose:
Adults and teenagers—Dose is usually 25 to 100 grams mixed with water.
Children 1 through 12 years of age—Dose is usually 25 to 50 grams mixed with water, or the dose may be based on body weight. It may be 0.5 to 1 gram per kilogram (kg) (0.23 to 0.45 gram per pound) of body weight mixed with water.
Children up to 1 year of age—Dose is usually 10 to 25 grams mixed with water, or the dose may be based on body weight. It may be 0.5 to 1 gram per kg (0.23 to 0.45 gram per pound) of body weight mixed with water.
CHAPS is an abbreviation for 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate. A related detergent, called CHAPSO, has the same basic chemical structure with an additional hydroxyl functional group; its full chemical name is 3-[(3-cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate.