POLYETHYLENE GLYCOL 4000
Polyethylene glycol 4000 (PEG 4000, Forlax) is a non-toxic, hydrosoluble, high-molecular polymer, which is not absorbed in the gastrointestinal tract following oral administration.
PEG 4000 acts as an osmotic agent that increases fecal water content. A number of clinical studies have demonstrated that PEG 4000 is effective in the treatment of constipation in adults and children (3–7).
Based on this administration schedule, the recommended daily dose of PEG 4000 in children from 6 months to 15 years is approximately 0.50 g/kg/d whatever the age, with a potential influence of the starting dose on the maintenance dose.
M.W range 3,000-3,700. Hygroscopic. Incompatible with strong oxidizing agents.