Categories: Lab Chemical-60
Product Short Description:

HATU FOR SYNTHESIS

Product Description:

During the synthesis of peptide nucleic acid (PNA) analogues, HATU was successfully used as a coupling reagent along with collidine, both in solution and solid phase. Furthermore, the synthetic route towards dehydrodidemnin B was improved by the use of HATU.

Product Application:

HATU(1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate) is a reagent used inpeptide couplingchemistry to generate an active ester from a carboxylic acid. HATU can be used along with Hünig's base(N,N-diisopropylethylamine, DIPEA) to form amide bonds.

Product Dose:

 A mide bonds are one of the underpinning linkages in all living systems and are fundamental within drug discovery. 

Product Note:

Current methods towards their synthesis frequently rely on the use of dipolar aprotic solvents; however, due to increasingly stringent regulations and growing societal pressures, safe and more sustainable alternatives are highly sought after. 

Free Delivery / Supply Locations : 
Oman, Bahrain, Abu Dhabi, Ajman, Al Ain, Dubai, Ras Al-Khaimah, Ras al Khaimah, Fujairah, Sharjah, Umm Al Quwain, Fujairah, Ruwais, Mina (Port) Zayed, Khalifa Port, Kizad, Port Rashid, Jebel Ali Port, DP WORLD, Jebel Ali Free Zone, Khor Fakkan Container Terminal, Port Rashid, Jebel Ali Port, Mina Kalid Port, Khor Fhakan Port ( Khawr Fakkan, Khawr al-Fakkan ), Sharjah Creek, Ajman, Port of Hamriyah, Mina Zayed Port, Mussafah port, Khalifa Port, Umm al-Nar Port, Um Al Quwain Port, Saqr Port, Port of Fujairah, Dibba Port, Jebel Dhanna, Mina Al Hamriya, Mina Rashid, All United Arab Emirates